Format

Send to

Choose Destination
FEBS Lett. 1989 Jan 2;242(2):211-4.

A unique signature identifies a family of zinc-dependent metallopeptidases.

Author information

1
Ludwig Institute for Cancer Research, Lausanne Branch, Epalinges, Switzerland.

Abstract

The primary sequence motif HExxH has been found in many zinc-dependent endopeptidases. We show that a larger signature comprising this sequence is common to most of the known zinc-dependent endopeptidases, and that the presence of the signature can be indicative of membership in the family. A search of the protein sequence databases for entries containing the signature retrieved several unexpected potential zinc endopeptidases.

PMID:
2914602
DOI:
10.1016/0014-5793(89)80471-5
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center