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J Am Coll Cardiol. 2017 Nov 14;70(20):2536-2551. doi: 10.1016/j.jacc.2017.09.1096.

Cardiovascular Complications of Cancer Therapy: Best Practices in Diagnosis, Prevention, and Management: Part 1.

Author information

1
Center for Precision Medicine, Department of Medicine, University of Missouri, Columbia, Missouri.
2
Department of Cardiology, University of Texas, MD Anderson Cancer Center, Houston, Texas.
3
Division of Cardiology, Virginia Common Wealth University, Richmond, Virginia.
4
Division of Cardiology, Rush University Medical Center, Chicago, Illinois.
5
Center for Precision Medicine, Department of Medicine, University of Missouri, Columbia, Missouri. Electronic address: yehet@health.missouri.edu.

Erratum in

Abstract

Modern cancer therapy has successfully cured many cancers and converted a terminal illness into a chronic disease. Because cancer patients often have coexisting heart diseases, expert advice from cardiologists will improve clinical outcome. In addition, cancer therapy can also cause myocardial damage, induce endothelial dysfunction, and alter cardiac conduction. Thus, it is important for practicing cardiologists to be knowledgeable about the diagnosis, prevention, and management of the cardiovascular complications of cancer therapy. In this first part of a 2-part review, we will review cancer therapy-induced cardiomyopathy and ischemia. This review is based on a MEDLINE search of published data, published clinical guidelines, and best practices in major cancer centers. With the number of cancer survivors expanding quickly, the time has come for cardiologists to work closely with cancer specialists to prevent and treat cancer therapy-induced cardiovascular complications.

KEYWORDS:

cancer therapy; cardiomyopathy; cardiovascular complication; ischemia

PMID:
29145954
PMCID:
PMC5825187
DOI:
10.1016/j.jacc.2017.09.1096
[Indexed for MEDLINE]
Free PMC Article

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