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Neuron. 2017 Nov 15;96(4):709-711. doi: 10.1016/j.neuron.2017.11.003.

GABAergic Synaptogenesis: A Case for Cooperation.

Author information

1
Institute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, 8057 Zürich, Switzerland; Neuroscience Centre Zurich (ZNZ), Winterthurerstrasse 190, 8057 Zürich, Switzerland.
2
Institute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, 8057 Zürich, Switzerland; Neuroscience Centre Zurich (ZNZ), Winterthurerstrasse 190, 8057 Zürich, Switzerland. Electronic address: tyagarajan@pharma.uzh.ch.

Abstract

Multiple cell-adhesion molecules contribute to synapse formation by mediating trans-synaptic interactions with presynaptic signaling molecules. In this issue of Neuron, Li et al. (2017) report cooperativity between Neuroligin2 and Slitrk3, exerting distinct effects on GABAergic synapse formation in immature and mature neurons.

PMID:
29144966
DOI:
10.1016/j.neuron.2017.11.003
[Indexed for MEDLINE]
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