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Nature. 2017 Nov 15;551(7680):313-320. doi: 10.1038/nature24624.

Progress in and promise of bacterial quorum sensing research.

Author information

1
School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia 30332-0230, USA.
2
Department of Microbiology, University of Washington School of Medicine, Seattle, Washington 98195-7735, USA.
3
Integrative Microbiology Research Center, South China Agricultural University, Guangzhou, China.

Abstract

This Review highlights how we can build upon the relatively new and rapidly developing field of research into bacterial quorum sensing (QS). We now have a depth of knowledge about how bacteria use QS signals to communicate with each other and to coordinate their activities. In recent years there have been extraordinary advances in our understanding of the genetics, genomics, biochemistry, and signal diversity of QS. We are beginning to understand the connections between QS and bacterial sociality. This foundation places us at the beginning of a new era in which researchers will be able to work towards new medicines to treat devastating infectious diseases, and use bacteria to understand the biology of sociality.

PMID:
29144467
PMCID:
PMC5870893
[Available on 2018-05-15]
DOI:
10.1038/nature24624
[Indexed for MEDLINE]
Free PMC Article

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