Format

Send to

Choose Destination
Clin Microbiol Rev. 2017 Nov 15;31(1). pii: e00029-17. doi: 10.1128/CMR.00029-17. Print 2018 Jan.

Candida auris: a Review of the Literature.

Author information

1
Public Health England, United Kingdom anna.jefferysmith@phe.gov.uk colin.brown@phe.gov.uk.
2
Barts Health NHS Trust, London, United Kingdom.
3
King's College Hospital NHS Foundation Trust, London, United Kingdom.
4
Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom.
5
Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.
6
Public Health England, United Kingdom.
7
Royal Free London NHS Foundation Trust, London, United Kingdom.

Abstract

The emerging pathogen Candida auris has been associated with nosocomial outbreaks on five continents. Genetic analysis indicates the simultaneous emergence of separate clades of this organism in different geographical locations. Invasive infection and colonization have been detected predominantly in patients in high-dependency settings and have garnered attention due to variable antifungal resistance profiles and transmission within units instituting a range of infection prevention and control measures. Issues with the identification of C. auris using both phenotypic and molecular techniques have raised concerns about detecting the true scale of the problem. This review considers the literature available on C. auris and highlights the key unknowns, which will provide direction for further work in this field.

KEYWORDS:

Candida auris; emerging infection; nosocomial transmission

PMID:
29142078
PMCID:
PMC5740969
DOI:
10.1128/CMR.00029-17
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for HighWire Icon for PubMed Central
Loading ...
Support Center