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Eur J Dermatol. 2017 Dec 1;27(6):573-578. doi: 10.1684/ejd.2017.3139.

Comparison of allergen responses based on the TRUE Test and IQ Chamber system in Korean patients.

Author information

1
Department of Dermatology, Hallym University Sacred Heart Hospital, Anyang, Korea.
2
Department of Dermatology, Hanyang University College of Medicine, Seoul, Korea.
3
Department of Dermatology, Dankook University College of Medicine, Cheonan, Korea.
4
Department of Dermatology, Busan National University College of Medicine, Busan, Korea.
5
Department of Dermatology, Hallym University College of Medicine, Seoul, Korea.
6
Department of Dermatology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
7
Department of Dermatology, National Medical Center, Seoul, Korea.
8
Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Korea.
9
Department of Dermatology, Sungkyunkwan University College of Medicine, Seoul, Korea.
10
Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea.
11
Department of Dermatology, Dongguk University College of Medicine, Kyungju, Korea.
12
College of Medicine, Catholic University of Korea, Seoul, Korea.
13
Department of Dermatology, University of Ulsan College of Medicine, Seoul, Korea.
14
Department of Dermatology, Ewha Womans University College of Medicine, Seoul, Korea.

Abstract

A comparison between responses to allergens based on the TRUE Test®(TT) and IQ® Chamber (IQC) in Europeans has been previously reported, however, no such study has been performed in Asians. To compare allergen responses using the TT and IQC (using the Korean standard series) in order to gather more information regarding the positive response rates for each allergen and the clinical value of IQC. Suspected contact dermatitis patients were enrolled and tested with 18 allergens using the TT and IQC. The test was performed in 214 patients. Simultaneous positive results for both tests were recorded in 242 cases (positive concordance rate: 66.7%). IQC yielded more positive results. Allergens with a high positive concordance rate were nickel sulphate (82.1%), thimerosal (78.6%), and p-phenylenediamine (73.3%). IQC mostly showed similar or higher positive rates than TT, with high concordance. We recommend the IQC method as a screening test in patients with suspected contact dermatitis. To compensate for possible false positive results, careful history taking and a different patch test should be performed when appropriate.

KEYWORDS:

IQ® Chamber; Korean standard series; TRUE Test®; concordance; patch test

PMID:
29138124
DOI:
10.1684/ejd.2017.3139
[Indexed for MEDLINE]

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