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Molecules. 2017 Nov 13;22(11). pii: E1957. doi: 10.3390/molecules22111957.

The Influence of Toothpaste Containing Australian Melaleuca alternifolia Oil and Ethanolic Extract of Polish Propolis on Oral Hygiene and Microbiome in Patients Requiring Conservative Procedures.

Author information

1
Doctoral Study, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia in Katowice, Pl. Traugutta 2, 41-800 Zabrze, Poland. tomasz_lek_dent@interia.pl.
2
Department of Microbiology and Immunology, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia in Katowice, Jordana 19, 41-808 Zabrze, Poland. amertas@sum.edu.pl.
3
Doctoral Study, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia in Katowice, Pl. Traugutta 2, 41-800 Zabrze, Poland. szczepa.karol@gmail.com.
4
Department of Prosthetic Dentistry, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia in Katowice, Plac Akademicki 17, 41-902 Bytom, Poland. rafstoma@gmail.com.
5
Department of Oral Surgery, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia in Katowice, Pl. Akademicki 17, 41-902 Bytom, Poland. pkownacki@sum.edu.pl.
6
Department of Oral Surgery, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia in Katowice, Pl. Akademicki 17, 41-902 Bytom, Poland. tallen@poczta.onet.pl.
7
Doctoral Study, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia in Katowice, Pl. Traugutta 2, 41-800 Zabrze, Poland. ewelina.kopczynska90@gmail.com.
8
Department of Oral Surgery, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia in Katowice, Pl. Akademicki 17, 41-902 Bytom, Poland. mwrzol@sum.edu.pl.
9
Department of Microbiology and Immunology, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia in Katowice, Jordana 19, 41-808 Zabrze, Poland. m.cisowska4@wp.pl.
10
Department of Microbiology and Immunology, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia in Katowice, Jordana 19, 41-808 Zabrze, Poland. eszliszka@sum.edu.pl.
11
Department of Microbiology and Immunology, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia in Katowice, Jordana 19, 41-808 Zabrze, Poland. zczuba@sum.edu.pl.
12
Department and Hospital of Craniomaxillofacial Surgery and Oral Surgery, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia in Katowice, Pl. Akademicki 17, 41-902 Bytom, Poland. niedzielska.konsultant@wp.pl.
13
Department of Oral Surgery, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia in Katowice, Pl. Akademicki 17, 41-902 Bytom, Poland. tmorawiec@sum.edu.pl.

Abstract

The study was based on the use of a toothpaste with antiphlogistic activity, containing Australian Melaleuca alternifolia oil (tea tree oil-TTO) and ethanolic extract of Polish propolis (EEP). Fifty-one patients with varying conditions of the gingiva were divided into two groups. The study group received the toothpaste with TTO and EEP, while the control group received the same toothpaste but without TTO and EEP. Approximal plaque index (API), simplified oral hygiene index (OHI-s) and modified sulcus bleeding index (mSBI) were assessed in three subsequent stages. During each examination, swabs were employed for microbiological inoculation. During the period of use of toothpastes with TTO and EEP, a significant reduction of the API was observed, as assessed upon the control visit after 7 days and after 28 days, compared to baseline. A statistically significant reduction of mSBI was observed after 7 and 28 days of using the toothpaste with TTO and EEP, as compared to the value upon the initial visit. Statistically significant differences in the OHI-s value were observed in the study group, which was using the active toothpaste. The use of a toothpaste containing TTO and EEP helps to maintain microbiome balance. The observed stabilisation of bacterial microflora confirms the beneficial activity of toothpaste containing EEP and TTO compared to the control group, where the lack of these substances contributed to the emergence of qualitative and quantitative changes in oral microbiome.

KEYWORDS:

oral hygiene; oral microbiome; propolis; tea tree oil

PMID:
29137160
PMCID:
PMC6150324
DOI:
10.3390/molecules22111957
[Indexed for MEDLINE]
Free PMC Article

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