Format

Send to

Choose Destination
Neurochirurgie. 2017 Dec;63(6):473-477. doi: 10.1016/j.neuchi.2017.06.002. Epub 2017 Nov 8.

[Platelet-rich plasma (PRP) and disc lesions: A review of the literature].

[Article in French]

Author information

1
Département des sciences de la motricité, université de Liège, allée des sports, B21, 4000 Liège, Belgique.
2
Département des sciences de la motricité, université de Liège, allée des sports, B21, 4000 Liège, Belgique; Service de medecine physique, réadaptation et traumatologie du sport, centre médical FIFA d'excellence, université de Liège, CHU de Liège, avenue de l'hôpital, B35, 4000 Liège, Belgique.
3
Service de radiodiagnostic, CHU de Liège, avenue de l'hôpital, B35, 4000 Liège, Belgique.
4
Service de medecine physique, réadaptation et traumatologie du sport, centre médical FIFA d'excellence, université de Liège, CHU de Liège, avenue de l'hôpital, B35, 4000 Liège, Belgique.
5
Service d'algologie, CHU de Liège, avenue de l'hôpital, B35, 4000 Liège, Belgique.
6
Service de chirurgie de l'appareil locomoteur, université de Liège, CHU de Liège, avenue de l'hôpital, B35, 4000 Liège, Belgique.
7
Service de neurochirurgie, CHU de Liège, avenue de l'hôpital, B35, 4000 Liège, Belgique.
8
Département des sciences de la motricité, université de Liège, allée des sports, B21, 4000 Liège, Belgique; Service de medecine physique, réadaptation et traumatologie du sport, centre médical FIFA d'excellence, université de Liège, CHU de Liège, avenue de l'hôpital, B35, 4000 Liège, Belgique. Electronic address: jfkaux@chu.ulg.ac.be.

Abstract

The spine has been the subject of extensive clinical research since it is the source of many painful complaints. However, there is little scientific evidence concerning the therapeutic proposals. During the course of life, the intervertebral disc degenerates, which over time diminishes its damping capacity and facilitates the expulsion of the nucleus pulposus through the annulus fibrosus. The degeneration of the intervertebral disc (DDI) is the origin of some back pain and various specific treatments have been developed. These include the infiltration at the center of the intervertebral disc of plasma rich platelet (PRP), composed of multiple growth factors which act on the disc degeneration. This treatment is recent and less invasive than surgery. Preliminary results seem promising. However, many gray areas and several parameters remained to be clarified. In an attempt to do this, a literature review was conducted based on bibliographic databases Pubmed, Medline and Scopus® using the following Mesh terms : PRP, platelet-rich plasma, intradiscal disc degeneration, disc, intradiscal, discogenic. This analysis reveals that at the present time, no reported study has a sufficient perspective to judge the effectiveness of the infiltration of PRP. Early harvest results will be used to set the limits of this treatment. Accordingly, it is therefore currently recommended to introduce PRP injection as a complementary solution to comprehensive care of the spine. Future research will need to generate randomized controlled studies including comparing the results with conservative treatment and measure the cost-benefit relationship.

KEYWORDS:

Discopathie; Discopathy; Disque intervertébral; Infiltration; Intervertebral disc; Plasma riche en plaquettes; Platelet-rich plasma

PMID:
29128087
DOI:
10.1016/j.neuchi.2017.06.002
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Masson (France)
Loading ...
Support Center