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Cureus. 2017 Sep 1;9(9):e1640. doi: 10.7759/cureus.1640.

Sporadic Meningioangiomatosis: A Series of Three Pediatric Cases.

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Neurosurgery, Wayne State University School of Medicine.
Pathology, Wayne State University School of Medicine.


Meningioangiomatosis (MA) is a rare benign, hamartomatous lesion within the leptomeninges and cerebral cortex. Three percent of intractable epileptic patients with tumor develop MA. It may be accompanied with neurofibromatosis type II, or it may occur sporadically. Three patients, age range of 2-16 years old, presented with episodes of seizure. The patients demonstrated no family history or stigmata of neurofibromatosis type II. Electroencephalogram (EEG) was unremarkable for epileptiform activity. Magnetic resonance imaging (MRI) revealed enhancing lesions within the frontal gyrus, the anterior cingulate gyrus, and the parietal lobe. Incomplete resection led to recurrence in one patient, and later, intraoperative ultrasound was used to achieve total resection in another patient. Each patient was seizure free on follow-up, and managed with anti-epileptic medication. Resection is the only curative treatment in 85% of MA cases. Complete resection is necessary for symptomatic treatment in cases of MA, as recurrence has been documented in this lesion. Intraoperative ultrasound is an effective imaging modality to ensure gross total resection of MA.


intraoperative ultrasound; meningioangiomatosis; meningioma; neurofibromatosis; nf2

Conflict of interest statement

The authors have declared that no competing interests exist.

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