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Nature. 1989 Jan 12;337(6203):138-43.

The bicoid protein is a positive regulator of hunchback transcription in the early Drosophila embryo.

Author information

1
Max Planck Institut für Entwicklungsbiologie, Abteilung III Genetik, Tübingen, FRG.

Abstract

A gradient in concentration of the protein product of the bicoid gene is a determinant of the anterior-posterior axis of Drosophila embryos. By binding upstream of the segmentation gene hunchback the bicoid protein controls its transcription, thereby translating maternal pattern-generating information into differential activation of zygotic gene expression.

PMID:
2911348
DOI:
10.1038/337138a0
[Indexed for MEDLINE]

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