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Curr Biol. 2017 Nov 6;27(21):R1168-R1170. doi: 10.1016/j.cub.2017.09.022.

Chromosome Segregation: Is the Spindle All About Microtubules?

Author information

1
Cell Biology and Biophysics Unit, European Molecular Biology Laboratory (EMBL), Meyerhofstrasse 1, 69117 Heidelberg, Germany.
2
Cell Biology and Biophysics Unit, European Molecular Biology Laboratory (EMBL), Meyerhofstrasse 1, 69117 Heidelberg, Germany. Electronic address: lenart@embl.de.

Abstract

The spindle segregates chromosomes in cell division and it has long been discussed whether it is microtubules alone that build this fundamental molecular machine. Recent work in mouse oocytes now shows that actin filaments co-assemble with microtubules to promote faithful chromosome segregation.

PMID:
29112871
DOI:
10.1016/j.cub.2017.09.022
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