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Nucleic Acids Res. 2018 Jan 4;46(D1):D1248-D1253. doi: 10.1093/nar/gkx1023.

BioModels: expanding horizons to include more modelling approaches and formats.

Author information

1
European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
2
Department of Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, University of Heidelberg, BioQuant, IPMB and DKFZ Heidelberg, Im Neuenheimer Feld 267, 69120 Heidelberg, Germany.
3
University of Rostock, Rostock, Germany.
4
Babraham Institute, Cambridge CB22 3AT, UK.

Abstract

BioModels serves as a central repository of mathematical models representing biological processes. It offers a platform to make mathematical models easily shareable across the systems modelling community, thereby supporting model reuse. To facilitate hosting a broader range of model formats derived from diverse modelling approaches and tools, a new infrastructure for BioModels has been developed that is available at http://www.ebi.ac.uk/biomodels. This new system allows submitting and sharing of a wide range of models with improved support for formats other than SBML. It also offers a version-control backed environment in which authors and curators can work collaboratively to curate models. This article summarises the features available in the current system and discusses the potential benefit they offer to the users over the previous system. In summary, the new portal broadens the scope of models accepted in BioModels and supports collaborative model curation which is crucial for model reproducibility and sharing.

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