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Mult Scler. 2018 Nov;24(13):1770-1772. doi: 10.1177/1352458517739990. Epub 2017 Nov 6.

The NAIMS cooperative pilot project: Design, implementation and future directions.

Author information

1
Division of Neurology, University of Toronto, Toronto, ON, Canada/Department of Neurology and Neurosurgery, Johns Hopkins University, Baltimore, MD, USA.
2
Laboratory for Neuroimaging Research, Partners Multiple Sclerosis Center, Departments of Neurology and Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
3
Department of Neurology and Neurosurgery, Johns Hopkins University, Baltimore, MD, USA.
4
Department of Neurology, University of California, San Francisco, San Francisco, CA, USA.
5
Translational Neuroradiology Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Rockville, MD, USA.
6
Departments of Diagnostic Radiology and Neurosurgery, Yale University, New Haven, CT, USA.
7
Department of Neurology, University of Southern California, Los Angeles, CA, USA.
8
Advanced Imaging Research Center, Oregon Health & Science University, Portland, OR, USA.
9
Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
10
Department of Neurology, Cedars-Sinai Medical Center, The North American Imaging in Multiple Sclerosis (NAIMS), Los Angeles, CA, USA.

Abstract

The North American Imaging in Multiple Sclerosis (NAIMS) Cooperative represents a network of 27 academic centers focused on accelerating the pace of magnetic resonance imaging (MRI) research in multiple sclerosis (MS) through idea exchange and collaboration. Recently, NAIMS completed its first project evaluating the feasibility of implementation and reproducibility of quantitative MRI measures derived from scanning a single MS patient using a high-resolution 3T protocol at seven sites. The results showed the feasibility of utilizing advanced quantitative MRI measures in multicenter studies and demonstrated the importance of careful standardization of scanning protocols, central image processing, and strategies to account for inter-site variability.

KEYWORDS:

MRI; North America; collaboration

PMID:
29106329
PMCID:
PMC5878974
[Available on 2019-11-01]
DOI:
10.1177/1352458517739990

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