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Biosci Biotechnol Biochem. 2017 Dec;81(12):2346-2352. doi: 10.1080/09168451.2017.1395681. Epub 2017 Nov 3.

Inhibitory effects of food additives derived from polyphenols on staphylococcal enterotoxin A production and biofilm formation by Staphylococcus aureus.

Author information

1
a School of Food and Nutritional Sciences , University of Shizuoka , Shizuoka , Japan.
2
b Department of Nutrition and Food Science , Ochanomizu University , Tokyo , Japan.

Abstract

In this study, we examined the inhibitory effects of 14 food additives derived from polyphenol samples on staphylococcal enterotoxin A (SEA) production and biofilm formation by Staphylococcus aureus. Tannic acid AL (TA), Purephenon 50 W (PP) and Polyphenon 70A (POP) at 0.25 mg/mL and Gravinol®-N (GN), Blackcurrant polyphenol AC10 (BP), and Resveratrol-P5 (RT) at 1.0 mg/mL significantly decreased SEA production by S. aureus C-29 (p < 0.05). TA, GN, BP, and RT significantly inhibited the expression of the sea gene in S. aureus C-29 (p < 0.05), while suppression attempts by PP and POP proved unsuccessful. After result analysis, it can be derived that TA, GN, BP, and RT inhibit the production of SEA. Of the six samples, each one significantly inhibited biofilm formation (p < 0.05). Food additives derived from polyphenols have viability to be used as a means to inhibit the enterotoxin production and control the biofilm formation of foodborne pathogens.

KEYWORDS:

Staphylococcus aureus; biofilm; food additives derived from polyphenol; staphylococcal enterotoxin A

PMID:
29098937
DOI:
10.1080/09168451.2017.1395681
[Indexed for MEDLINE]

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