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J Small Anim Pract. 2018 Jan;59(1):27-31. doi: 10.1111/jsap.12775. Epub 2017 Oct 31.

Long-lived immunity to canine core vaccine antigens in UK dogs as assessed by an in-practice test kit.

Author information

1
Moreton Morrell College, Moreton Morrell, Warwickshire, CV35 9BL, UK.
2
Medivet, Watford, Hertfordshire, WD24 7UY, UK.
3
Hyde Park Veterinary Centre, London, W2 2AE, UK.
4
School of Veterinary Sciences, University of Bristol, Langford, North Somerset, BS40 5DU, UK.

Abstract

OBJECTIVES:

To determine the utility of an in-practice test kit to detect protective serum antibody against canine distemper virus, canine adenovirus and canine parvovirus type 2 in a sample of the UK dog population.

MATERIALS AND METHODS:

Serum samples from 486 dogs, last vaccinated between less than 1 month and 124 months previously, were tested with the VacciCheck™ test kit for protective antibodies against distemper, adenovirus and parvovirus type 2.

RESULTS:

A high proportion of the dogs tested (93·6%) had protective antibody against all three of the core vaccine antigens: 95·7% of the dogs were seropositive against canine distemper virus, 97·3% against canine adenovirus and 98·5% against canine parvovirus type 2. The small number of dogs that were seronegative for one or more of the antigens (n = 31) may have had waning of previous serum antibody or may have been rare genetic non-responders to that specific antigen.

CLINICAL SIGNIFICANCE:

UK veterinarians can be reassured that triennial revaccination of adult dogs with core vaccines provides long-lived protective immunity. In-practice serological test kits are a valuable tool for informing decision-making about canine core revaccination.

PMID:
29087557
DOI:
10.1111/jsap.12775
[Indexed for MEDLINE]

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