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Nat Plants. 2017 Nov;3(11):854-858. doi: 10.1038/s41477-017-0039-z. Epub 2017 Oct 30.

Arabidopsis BTB/POZ protein-dependent PENETRATION3 trafficking and disease susceptibility.

Author information

1
Umeå Plant Science Centre, Department of Plant Physiology, Umeå University, SE-90 187, Umeå, Sweden.
2
Department of Biology, Plant Biology Unit, University of Fribourg, Rue Albert-Gockel 3, PER04, CH-1700, Fribourg, Switzerland.
3
Department of Molecular Biology, Max Planck Institute for Developmental Biology, Spemannstr. 35, DE-72076, Tübingen, Germany.
4
Umeå Plant Science Centre, Department of Plant Physiology, Umeå University, SE-90 187, Umeå, Sweden. markus.grebe@uni-potsdam.de.
5
Institute of Biochemistry and Biology, Department of Plant Physiology, University of Potsdam, Karl-Liebknecht-Str. 24-25, Building 20, DE-14476, Potsdam-Golm, Germany. markus.grebe@uni-potsdam.de.

Abstract

The outermost cell layer of plant roots (epidermis) constantly encounters environmental challenges. The epidermal outer plasma membrane domain harbours the PENETRATION3 (PEN3)/ABCG36/PDR8 ATP-binding cassette transporter that confers non-host resistance to several pathogens. Here, we show that the Arabidopsis ENDOPLASMIC RETICULUM-ARRESTED PEN3 (EAP3) BTB/POZ-domain protein specifically mediates PEN3 exit from the endoplasmic reticulum and confers resistance to a root-penetrating fungus, providing prime evidence for BTB/POZ-domain protein-dependent membrane trafficking underlying disease resistance.

PMID:
29085068
DOI:
10.1038/s41477-017-0039-z
[Indexed for MEDLINE]

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