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Patient Prefer Adherence. 2017 Oct 16;11:1755-1766. doi: 10.2147/PPA.S145562. eCollection 2017.

Comparison of patients' tolerance between computed tomography enterography and double-balloon enteroscopy.

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Department of Gastroenterology, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, People's Republic of China.
Contributed equally



Computed tomography enterography (CTE) and double-balloon enteroscopy (DBE) are widely used in diagnosis of small bowel diseases. Both of these examinations bring discomfort to patients. The aim of this study was to compare patients' tolerance and preference between CTE and DBE.


From August 1, 2014 to December 31, 2016, patients with suspected or known small bowel diseases who underwent both CTE and DBE were prospectively enrolled in our study. They were asked to fill out a questionnaire evaluating discomfort of the procedure after each examination.


One hundred and seven patients completed our study. Abdominal distension, painfulness, tenesmus, general discomfort, prolonged duration, difficulty in completing the test, and discomfort after the examination were significantly lower with CTE than with DBE (P<0.001, respectively). Mannitol intake (47.7%), bowel preparation (31.9%), and radiation exposure (15.0%) were regarded as the three most intolerable burdens in CTE. Painfulness (38.3%), bowel preparation (26.2%), and invasiveness (16.8%) were considered as the three most unacceptable parts of DBE. More patients (61.7%) preferred to repeat CTE rather than DBE (P<0.001).


Compared to DBE, CTE was a more tolerable and less burdensome examination and enjoyed higher preference by most patients.


computed tomography enterography; double-balloon enteroscopy; tolerance and preference

Conflict of interest statement

Disclosure The authors report no conflicts of interest in this work.

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