Noninsulin Diabetes Medications

Nurs Clin North Am. 2017 Dec;52(4):523-537. doi: 10.1016/j.cnur.2017.07.003. Epub 2017 Oct 5.

Abstract

Pharmacotherapy for diabetes has changed greatly owing to drugs and drug classes available. There are 11 classes of noninsulin diabetes medications available in the United States. With the use of 1 drug alone or in combination with different drugs, it is possible to improve glycemic control in patients with diabetes. Important properties of antidiabetic agents play a role in the choice of that particular medication for individual patients. Prescribing a diabetes medication regimen is based careful assessment of patient needs, and consideration of the medication's efficacy, impact on weight, hypoglycemia risk, potential side effects, cost, and patient preferences.

Keywords: Alpha-glucosidase inhibitors; Biguanides; Diabetes medications; Dipeptidyl peptidase 4 inhibitors; Glucagon like peptide–1 agonists; Meglitinides; Selective sodium-glucose transporter-2 inhibitors; Sulfonylureas.

Publication types

  • Review

MeSH terms

  • Diabetes Complications / nursing*
  • Diabetes Complications / prevention & control
  • Diabetes Mellitus, Type 2 / drug therapy*
  • Diabetes Mellitus, Type 2 / nursing*
  • Evidence-Based Nursing
  • Glycated Hemoglobin / drug effects
  • Humans
  • Hypoglycemic Agents / therapeutic use*
  • Medication Therapy Management / organization & administration
  • United States

Substances

  • Glycated Hemoglobin A
  • Hypoglycemic Agents