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Arthritis Care Res (Hoboken). 2017 Oct 26. doi: 10.1002/acr.23452. [Epub ahead of print]

Low-dose glucocorticoids in rheumatoid arthritis: blurring the line between therapeutic dose and substitution therapy?

Author information

1
Center for Musculoskeletal Surgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.
2
Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
3
Department of Psychology, Health and Technology, University of Twente, Enschede, The Netherlands.
4
Amsterdam Rheumatology& Immunology Center, VU University Medical Center, Amsterdam, The Netherlands.

Abstract

We would like to thank Masi and colleagues for their interest in our paper as well as for the interesting comments regarding the potential usefulness of neuroendocrine immune (NEI) testing in patients with rheumatoid arthritis (RA). When the first patient with rheumatoid arthritis (RA) was treated with glucocorticoids (GCs) in 1948, the effect was just overwhelming for that time. This article is protected by copyright. All rights reserved.

KEYWORDS:

circadian rhythm; glucocorticoids; hypothalamic-pituitary-adrenal axis; neuroendocrine immune testing; rheumatoid arthritis

PMID:
29073333
DOI:
10.1002/acr.23452
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