The child's behavior during inhalational induction and its impact on the anesthesiologist's sevoflurane exposure

Paediatr Anaesth. 2017 Dec;27(12):1247-1252. doi: 10.1111/pan.13269. Epub 2017 Oct 25.

Abstract

Background: Sevoflurane is commonly used for inhalational inductions in children, but the personnel's exposure to it is potentially harmful. Guidance to reduce gas pollution refers mainly to technical aspects, but the impact of the child's behavior has not yet been studied.

Aims: The purpose of this study was to determine how child behavior, according to the Frankl Behavioral Scale, affects the amount of waste sevoflurane in anesthesiologists' breathing zones.

Methods: Sixty-eight children aged 36-96 months undergoing elective ENT surgery were recruited for this prospective, observational investigation. After oral midazolam premedication (0.5 mg/kg body weight), patients obtained sevoflurane using a facemask with an inspiratory concentration of 8 Vol.% in 100% oxygen (flow 10 L/min). Ventilation was manually supported and a venous catheter was placed. The inspiratory sevoflurane concentration was reduced, and remifentanil and propofol were administered before the facemask was removed and a cuffed tracheal tube inserted. The child's behavior toward the operating room personnel during induction was evaluated by the anesthesiologist (Frankl Behavioral Scale: 1-2 = negative behavior, 3-4 = positive behavior). During induction mean (c¯mean) and maximum (c¯max), sevoflurane concentrations were determined in the anesthesiologist's breathing zone by continuous photoacoustic gas monitoring.

Results: Mean and maximum sevoflurane concentrations were c¯mean = 4.38 ± 4.02 p.p.m and c¯max = 70.06 ± 61.08 p.p.m in patients with positive behaviors and sufficient premedications and c¯mean = 12.63 ± 8.66 p.p.m and c¯max = 242.86 ± 139.91 p.p.m in children with negative behaviors and insufficient premedications (c¯mean: P < .001; c¯max: P < .001).

Conclusion: Negative behavior was accompanied by significantly higher mean and maximum sevoflurane concentrations in the anesthesiologist's breathing zone compared with children with positive attitudes. Consequently, the status of premedication influences the amount of sevoflurane pollution in the air of operating rooms.

Keywords: Frankl Behavioral Scale; Photoacoustic Gas Monitor; gas pollution; inhalational induction; premedication; sevoflurane exposure.

MeSH terms

  • Air Pollution, Indoor
  • Anesthesia, Inhalation*
  • Anesthesiologists*
  • Anesthetics, Inhalation / analysis*
  • Child
  • Child Behavior*
  • Child, Preschool
  • Environmental Monitoring
  • Female
  • Humans
  • Hypnotics and Sedatives
  • Male
  • Methyl Ethers / analysis*
  • Occupational Exposure / statistics & numerical data*
  • Operating Rooms
  • Otorhinolaryngologic Surgical Procedures
  • Piperidines
  • Preanesthetic Medication
  • Propofol
  • Prospective Studies
  • Remifentanil
  • Respiration, Artificial
  • Sevoflurane

Substances

  • Anesthetics, Inhalation
  • Hypnotics and Sedatives
  • Methyl Ethers
  • Piperidines
  • Sevoflurane
  • Remifentanil
  • Propofol