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PLoS Negl Trop Dis. 2017 Oct 24;11(10):e0006005. doi: 10.1371/journal.pntd.0006005. eCollection 2017 Oct.

Giardiasis as a neglected disease in Brazil: Systematic review of 20 years of publications.

Author information

1
Biology Department, Georgetown University, Washington DC, United States of America.
2
U.S. FDA, OARSA, CFSAN, Laurel, MD, United States of America.
3
Basic Pathology Department, Biological Sciences Sector, Federal University of Paraná, Curitiba, Brazil.
4
Department of Bioinformatics and Genomics, University of North Carolina at Charlotte, Charlotte, NC, United States of America.
5
Animal Biology Department, Biology Institute, University of Campinas, Campinas, Brazil.

Abstract

INTRODUCTION:

Giardiasis is an intestinal infection that affects more than two hundred million people annually worldwide; it is caused by the flagellated protozoan Giardia duodenalis. In tropical countries and in low or middle-income settings, like Brazil, its prevalence can be high. There is currently no systematic review on the presence of G. duodenalis in patients, animals or water sources in Brazil.

METHODS:

This systematic review was performed according to recommendations established by Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). As databases for our searches, we have used PubMed, Embase, Scopus and the Brazilian database SciELO using the keywords «Giardia*» and «Brazil».

RESULTS:

This systematic review identified research studies related to G. duodenalis in water, giardiasis in animals, prevalence of giardiasis across Brazilian regions, genotyping of strains isolated in humans, and giardiasis in indigenous populations. We also propose a network of G. duodenalis transmission in Brazil based on genotypes analyses.

CONCLUSION:

This is the first time within the last twenty years that a review is being published on the occurrence of G. duodenalis in Brazil, addressing relevant issues such as prevalence, molecular epidemiology and analytical methods for parasite detection.

PMID:
29065126
PMCID:
PMC5678545
DOI:
10.1371/journal.pntd.0006005
[Indexed for MEDLINE]
Free PMC Article

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