STING Senses Microbial Viability to Orchestrate Stress-Mediated Autophagy of the Endoplasmic Reticulum

Affiliations

• ¹ The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY 10021, USA; Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY 10021, USA.
• ² Department of Medicine, Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
• ³ Brain Tumor Nanotechnology Laboratory, Department of Neurosurgery, Tisch Cancer Institute, The Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
• ⁴ Immunity, Inflammation, and Disease Laboratory, Inflammation and Autoimmunity Group, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.
• ⁵ Office of Collaborative Science, Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA.
• ⁶ Department of Medicine, University of Wisconsin-Madison, Madison, WI 53705, USA.
• ⁷ Department of Molecular Biology and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
• ⁸ Department of Genetics and Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
• ⁹ The Leona M. and Harry B. Helmsley Charitable Trust, New York, NY 10169, USA.
• ¹⁰ Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
• ¹¹ The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY 10021, USA; Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY 10021, USA; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY 10021, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, Cornell University, New York, NY 10021, USA; Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, Cornell University, New York, NY 10021, USA. Electronic address: jmblander@med.cornell.edu.