Format

Send to

Choose Destination
Nature. 1988 Dec 22-29;336(6201):744-9.

Activation and repression of transcription by homoeodomain-containing proteins that bind a common site.

Author information

1
Department of Biochemistry and Biophysics, University of California, San Francisco 94143.

Abstract

The product of the fushi tarazu (ftz) gene is shown to be a site-dependent activator of transcription. In vitro-defined binding sites act as ftz-dependent enhancers in cultured cells. Another homoeodomain-containing protein, the engrailed gene product, competes for homoeodomain-binding sites and counteracts ftz activation.

PMID:
2905023
PMCID:
PMC2868829
DOI:
10.1038/336744a0
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Nature Publishing Group Icon for PubMed Central
Loading ...
Support Center