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Gigascience. 2017 Nov 1;6(11):1-6. doi: 10.1093/gigascience/gix100.

Parallel sequencing lives, or what makes large sequencing projects successful.

Author information

1
Gene Regulation, Stem Cells and Cancer Program, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST), Dr. Aiguader 88, 08003 Barcelona, Spain.
2
Universitat Pompeu Fabra (UPF), Barcelona, Spain.
3
CNAG-CRG, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST), Dr. Aiguader 88, 08003 Barcelona, Spain.
4
ICREA, Pg. Lluis Companys 23, 08010 Barcelona, Spain.

Abstract

T47D_rep2 and b1913e6c1_51720e9cf were 2 Hi-C samples. They were born and processed at the same time, yet their fates were very different. The life of b1913e6c1_51720e9cf was simple and fruitful, while that of T47D_rep2 was full of accidents and sorrow. At the heart of these differences lies the fact that b1913e6c1_51720e9cf was born under a lab culture of Documentation, Automation, Traceability, and Autonomy and compliance with the FAIR Principles. Their lives are a lesson for those who wish to embark on the journey of managing high-throughput sequencing data.

KEYWORDS:

FAIR Principles; bioinformatics; high-throughput sequencing; management and analysis best practices

PMID:
29048533
PMCID:
PMC5714127
DOI:
10.1093/gigascience/gix100
[Indexed for MEDLINE]
Free PMC Article

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