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J Allergy Clin Immunol. 2018 Feb;141(2):505-517. doi: 10.1016/j.jaci.2017.09.022. Epub 2017 Oct 16.

Eosinophils and eosinophil-associated diseases: An update.

Author information

1
Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
2
Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill. Electronic address: bruce.bochner@northwestern.edu.

Abstract

The goal of this series is to offer a survey of the latest literature for clinicians and scientists alike, providing a list of important recent advances relevant to the broad field of allergy and immunology. This particular assignment was to cover the topic of eosinophils. In an attempt to highlight major ideas, themes, trends, and advances relevant to basic and clinical aspects of eosinophil biology, a search of articles published since 2015 in the Journal of Allergy and Clinical Immunology and other high-impact journals was performed. Articles were then reviewed and organized, and then key findings were summarized. Given space limitations, many outstanding articles could not be included, but the hope is that what follows provides a succinct overview of recently published work that has significantly added to our knowledge of eosinophils and eosinophil-associated diseases.

KEYWORDS:

Eosinophilopoiesis; adipose tissue; apoptosis; asthma; biologicals; chronic rhinosinusitis with nasal polyposis; eosinophil subsets; eosinophilic gastrointestinal disorder; granule biogenesis; immunoregulation

PMID:
29045815
PMCID:
PMC5803328
[Available on 2019-02-01]
DOI:
10.1016/j.jaci.2017.09.022

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