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Lancet. 1988 Dec 24-31;2(8626-8627):1451-3.

Role of subcutaneous apomorphine in parkinsonian voiding dysfunction.

Author information

1
Department of Urology, Middlesex Hospital, London.

Abstract

Ten patients with Parkinson's disease and urinary symptoms underwent urodynamic assessments before and after subcutaneous administration of the dopamine receptor agonist apomorphine. Voiding efficiency improved after apomorphine injection, with an increase in mean and maximum flow rates in nine patients and reduction in post-micturition residual volume in six. Although the effect on detrusor behaviour was variable, subcutaneous apomorphine may be of use in both the assessment and treatment of voiding dysfunction in patients with Parkinson's disease.

PMID:
2904571
DOI:
10.1016/s0140-6736(88)90932-4
[Indexed for MEDLINE]

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