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Acad Med. 2017 Oct 17. doi: 10.1097/ACM.0000000000002029. [Epub ahead of print]

OneFlorida Clinical Research Consortium: Linking a Clinical and Translational Science Institute With a Community-Based Distributive Medical Education Model.

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E. Shenkman is professor, Department of Health Outcomes and Policy, College of Medicine, University of Florida, Gainesville, Florida; ORCID: M. Hurt is professor of biomedical sciences and associate dean for research, College of Medicine, Florida State University, Tallahassee, Florida. W. Hogan is professor and director of biomedical informatics, Department of Health Outcomes and Policy, College of Medicine, University of Florida, Gainesville, Florida. O. Carrasquillo is professor and director of medicine and health services research and policy, Leonard M. Miller School of Medicine, University of Miami, Miami, Florida. S. Smith is chief scientific officer, Florida Hospital, Orlando, Florida A. Brickman is director of research, Health Choice Network, Doral, Florida. D. Nelson is professor and director, Clinical and Translational Science Institute, Department of Medicine, College of Medicine, University of Florida, Gainesville, Florida.



Developing a national pragmatic clinical trial infrastructure is central to understanding the effectiveness of interventions applied under usual conditions and where people receive health care. To address this challenge, three Florida universities- the University of Florida Clinical and Translational Science Institute, Florida State University (with its community-based distributive medical education model), and the University of Miami-created (2010-2013) a statewide consortium, the OneFlorida Clinical Research Consortium, to support the conduct of pragmatic clinical trials and provide mentored research experiences for medical and graduate students in real-world practice settings.


One Florida has four programs, which report to a steering committee with membership from each partner, community members, and the state Medicaid agency and Department of Health to ensure shared governance. The Clinical Research Program provides support to conduct research in the network and uses champions to engage community clinicians. The Citizen Scientist Program has community members who provide input on health topics of importance to them, study design, recruitment and retention strategies, and the interpretation of findings. The OneFlorida Data Trust Program contains electronic health record and health care claims data for 10.6 million Floridians. The Minority Education Program, in collaboration with three historically black colleges and universities, offers minority junior faculty mentoring in pragmatic clinical trials and implementation science.


OneFlorida has implemented 27 studies with diverse patient populations and in diverse community practice settings.


To identify evidence-based best practices from the clinical trials conducted in the network, foster their implementation, and expand research training opportunities.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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