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Clin Exp Dermatol. 2018 Mar;43(2):164-167. doi: 10.1111/ced.13287. Epub 2017 Oct 15.

Melanoma arising from a plaque-type blue naevus with subcutaneous cellular nodules of the scalp.

Author information

1
Department of Dermatology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
2
Section of Dermatology, Department of Medical, Surgical and Neurosciences, University of Siena, Siena, Italy.
3
Department of Medical Biotechnologies, University of Siena, Siena, Italy.
4
Section of Plastic Surgery Dermatology, Department of Medical, Surgical and Neurosciences, University of Siena, Siena, Italy.

Abstract

Plaque-type blue naevus (PTBN) is a very rare variant of blue naevus (BN). The potential malignancy of subcutaneous cellular nodules (SCN) in PTBN was discovered in 2012, and there is currently no clear consensus on prognostic factors or management guidelines of such lesions. PTBN on the scalp have not been described in the literature. We report the clinical, histopathological and immunohistological features of a 50-year-old man who presented with a 30-year history of scalp PTBN, with malignant proliferation of nodular elements and fatal outcome 8 years later. This case suggests that long-term monitoring of patients with PTBN is required. Early surgical removal of such lesions should be considered, especially in the presence of any case of enlargement or change.

PMID:
29034495
DOI:
10.1111/ced.13287
[Indexed for MEDLINE]

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