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J Diabetes. 2018 Apr;10(4):328-337. doi: 10.1111/1753-0407.12614. Epub 2017 Dec 11.

Resistance training reduces metabolic syndrome and inflammatory markers in older women: A randomized controlled trial.

Author information

1
Physical Education Department, Metabolism, Nutrition, and Exercise Laboratory, Londrina State University, Londrina, Brazil.
2
Physical Education Department, Exercise Physiology Laboratory, Faculty of Physical Education, University of Campinas, Campinas, Brazil.
3
Department of Pathology, Botucatu School of Medicine, São Paulo State University, Botucatu, Brazil.
4
Exercise and Nutrition Metabolism Center from the Department of Public Health, Botucatu School of Medicine, São Paulo State University, Botucatu, Brazil.
5
Center for Research in Health Sciences, University of Northern Parana, Londrina, Brazil.
6
Clinical Analyses Laboratory, Londrina State University, Londrina, Brazil.
7
Exercise and Health Laboratory, Interdisciplinary Centre for the Study of Human Performance, Faculty of Human Kinetics, University of Lisbon, Lisbon, Portugal.

Abstract

BACKGROUND:

This study analyzed the effects of a 12-week resistance training (RT) program without dietary interventions on metabolic syndrome (MetS) components and inflammatory biomarkers in older women.

METHODS:

Fifty-three older women (mean [±SD] age 70.4 ± 5.7 years; mean body mass index 26.7 ± 4.0 kg/m2 ) were randomly assigned to a training group (TG; n = 26) that performed 12 weeks of an RT program or a control group (CG; n = 27) that did not perform any type of physical exercise over the same period. Body composition (dual energy X-ray absorptiometry), muscular strength (one-repetition maximum tests), blood pressure (BP), and blood sample measurements were performed before and after intervention.

RESULTS:

After the 12-week period, there were significantly reductions (P < 0.05) in glucose levels (-20.4% vs -0.3%), waist circumference (-1.5% vs +2.0%), and systolic BP (-6.2% vs +0.9%), and complete normalization of MetS prevalence (18% at baseline vs. 0% after 12-weeks RT) in the TG. Moreover, C-reactive protein and tumor necrosis factor-α concentrations decreased in the TG (-28.6% and -21.6%, respectively), but increased in the CG (+34.5% and +13.3%, respectively). In addition there were positive improvements in the MetS Z-score in the TG but not CG (-21.6% vs +13.3%, respectively).

CONCLUSION:

The results suggest that a 12-week RT program seems to effectively reduce MetS components and inflammatory biomarkers in older women, regardless of dietary intervention. The RT-induced adaptations in body composition and inflammatory biomarkers appear to be related to healthy adaptations in risk factors for MetS.

KEYWORDS:

body composition; low-grade inflammation; randomized controlled trial; strength training; 低度炎症; 力量训练; 身体组份; 随机对照试验

PMID:
29031002
DOI:
10.1111/1753-0407.12614
[Indexed for MEDLINE]

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