This article describes some practical applications of critical care ultrasonography that are of interest to the frontline intensivist. Instead of presenting a standard state of the art review article, we present 3 typical clinical cases where combined echocardiography, lung ultrasonography, and other ultrasonography techniques were helpful to the critical care team. The manuscript includes a variety figures and video clips that illustrate the utility of critical care ultrasonography in guiding diagnosis and management of the critically ill patient.