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J Occup Environ Med. 2018 Feb;60(2):174-179. doi: 10.1097/JOM.0000000000001194.

Exploring Associations Between Postural Balance and Levels of Urinary Organophosphorus Pesticide Metabolites.

Author information

1
Industrial and Systems Engineering, Virginia Tech, Blacksburg, Virginia (Dr Kim, Dr Nussbaum); Department of Radiology (Dr Laurienti); Department of Biostatistical Science (Dr Chen); Department of Epidemiology and Prevention (Dr Quandt), Division of Public Health Sciences; Department of Environmental and Occupational Health, Rollins School of Public Health of Emory University, Atlanta, Georgia (Dr Barr); and Department of Family and Community Medicine (Dr Arcury), Center for Worker Health, Wake Forest School of Medicine, Winston-Salem, North Carolina.

Abstract

OBJECTIVE:

Apply a data-driven approach to explore associations between postural balance and pesticide exposure among Latino farmworkers and non-farmworkers.

METHODS:

Lasso-regularized, generalized linear models were used to examine associations between postural control measures in four experimental conditions (2 visual × 2 cognitive difficulty) and dialkylphosphate (DAP) urinary metabolite levels.

RESULTS:

Obtained models generally performed poorly at explaining postural control measures. However, when both visual and cognitive conditions were altered-the most challenging balance condition-models for some postural balance measures contained several DAP metabolites and had relatively better fits.

CONCLUSIONS:

The current results were equivocal regarding associations between postural control measures and DAP metabolite concentrations. However, farmworker status appears to be an important variable in understanding this association. Future work should use a posturally- and cognitively-challenging test condition to reveal any potential associations.

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