Presence of HTLV-I proviral DNA in patients with adult T-cell leukemia/lymphoma in Taiwan

T T Kuo; H Sato; P Dunn; L Y Shih; T Eimoto; M Kikuchi; Y Maeda

doi:10.1002/1097-0142(19880815)62:4<702::aid-cncr2820620409>3.0.co;2-i

Presence of HTLV-I proviral DNA in patients with adult T-cell leukemia/lymphoma in Taiwan

Cancer. 1988 Aug 15;62(4):702-4. doi: 10.1002/1097-0142(19880815)62:4<702::aid-cncr2820620409>3.0.co;2-i.

Authors

T T Kuo¹, H Sato, P Dunn, L Y Shih, T Eimoto, M Kikuchi, Y Maeda

Affiliation

¹ Department of Pathology, Chang Gung Medical College, Taipei, Taiwan, Republic of China.

PMID: 2899453
DOI: 10.1002/1097-0142(19880815)62:4<702::aid-cncr2820620409>3.0.co;2-i

Abstract

Human T-lymphotropic virus-I (HTLV-I) proviral DNA was demonstrated in the leukemic cells of two newly identified cases of adult T-cell leukemia/lymphoma (ATL) in Taiwan by the Southern blot hybridization method. Therefore, the ATL cases diagnosed clinicopathologically in Taiwan were, for the first time, documented to be definitely related to HTLV-I.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Antibodies, Viral / analysis
DNA, Viral / analysis*
Deltaretrovirus / genetics
Deltaretrovirus Antibodies
Deltaretrovirus Infections / epidemiology
Deltaretrovirus Infections / microbiology*
Humans
Male
Middle Aged
Serologic Tests
Taiwan

Substances

Antibodies, Viral
DNA, Viral
Deltaretrovirus Antibodies