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J Am Soc Hypertens. 2017 Nov;11(11):709-715. doi: 10.1016/j.jash.2017.09.008. Epub 2017 Sep 27.

Air pollution and arterial hypertension. A new risk factor is in the air.

Author information

1
Department of Cardiology, Hypertension Excellence Centre-ESH, LAIKO General Hospital, Athens, Greece. Electronic address: easanidas@yahoo.gr.
2
Department of Cardiology, Hypertension Excellence Centre-ESH, LAIKO General Hospital, Athens, Greece.
3
Department of Cardiology, Hypertension Excellence Centre-ESH, KAT General Hospital, Athens, Greece.
4
Department of Cardiology, Hippokrateion Hospital, University of Athens, Athens, Greece.
5
Hypertension and Cardiovascular Research Clinic, Veterans Affairs and Georgetown University Medical Centers, Washington DC, USA.

Abstract

Air pollution is one of the greatest environmental threats and has been implicated for several adverse cardiovascular effects including arterial hypertension (HTN). However, the exact relationship between air pollution exposure and HTN is still unclear. Air contamination provokes oxidative stress, systemic inflammation, and autonomic nervous system imbalance that subsequently induce endothelial dysfunction and vasoconstriction leading to increased blood pressure. The aim of this review was to describe the potential mechanisms by which air pollution contributes to HTN and to summarize the consequences of short- and long-term exposure.

KEYWORDS:

Air pollution; cardiovascular effects; hypertension

PMID:
28989071
DOI:
10.1016/j.jash.2017.09.008
[Indexed for MEDLINE]

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