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Nervenarzt. 2017 Nov;88(11):1323-1334. doi: 10.1007/s00115-017-0421-0.

[Correct treatment of mood disorders with lithium].

[Article in German]

Author information

1
Klinik und Poliklinik für Psychiatrie und Psychotherapie, Universitätsklinikum Carl Gustav Carus an der Technischen Universität Dresden, Fetscherstr. 74, 01307, Dresden, Deutschland.
2
Klinik und Poliklinik für Psychiatrie und Psychotherapie, Universitätsklinikum Carl Gustav Carus an der Technischen Universität Dresden, Fetscherstr. 74, 01307, Dresden, Deutschland. michael.bauer@uniklinikum-dresden.de.

Abstract

Due to their unique therapeutic effects and high efficacy, lithium salts are recommended in guidelines, particularly for the treatment of mood disorders; however, despite the therapeutic efficacy lithium treatment is underutilized in the treatment of these disorders. The therapeutic efficacy of lithium is contrasted by a narrow therapeutic range and a potential risk of intoxication, which is why close drug monitoring is necessary during lithium treatment. Furthermore, lithium therapy requires well-founded knowledge about patient selection with respect to approved areas of administration and indications. This review article summarizes clinically relevant knowledge of lithium treatment to improve treatment of patients with mood disorders and to increase patient safety when using lithium.

KEYWORDS:

Bipolar disorders; Depressive disorders; Drug interactions; Drug monitoring; Prevention and control, mood disorders

PMID:
28980047
DOI:
10.1007/s00115-017-0421-0
[Indexed for MEDLINE]

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