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World J Gastroenterol. 2017 Sep 14;23(34):6273-6280. doi: 10.3748/wjg.v23.i34.6273.

Predictive factors for the failure of endoscopic stent-in-stent self-expandable metallic stent placement to treat malignant hilar biliary obstruction.

Author information

1
Department of Gastroenterology, Fukushima Medical University, School of Medicine, Fukushima 960-1247, Japan.
2
Department of Gastroenterology, Fukushima Medical University, School of Medicine, Fukushima 960-1247, Japan. daccho@fmu.ac.jp.
3
Department of Endoscopy, Fukushima Medical University Hospital, Fukushima 960-1247, Japan.

Abstract

AIM:

To investigate the factors predictive of failure when placing a second biliary self-expandable metallic stents (SEMSs).

METHODS:

This study evaluated 65 patients with an unresectable malignant hilar biliary obstruction who were examined in our hospital. Sixty-two of these patients were recruited to the study and divided into two groups: the success group, which consisted of patients in whom a stent-in-stent SEMS had been placed successfully, and the failure group, which consisted of patients in whom the stent-in-stent SEMS had not been placed successfully. We compared the characteristics of the patients, the stricture state of their biliary ducts, and the implemented endoscopic retrograde cholangiopancreatography (ERCP) procedures between the two groups.

RESULTS:

The angle between the target biliary duct stricture and the first implanted SEMS was significantly larger in the failure group than in the success group. There were significantly fewer wire or dilation devices (ERCP catheter, dilator, or balloon catheter) passing the first SEMS cell in the failure group than in the success group. The cut-off value of the angle predicting stent-in-stent SEMS placement failure was 49.7 degrees according to the ROC curve (sensitivity 91.7%, specificity 61.2%). Furthermore, the angle was significantly smaller in patients with wire or dilation devices passing the first SEMS cell than in patients without wire or dilation devices passing the first SEMS cell.

CONCLUSION:

A large angle was identified as a predictive factor for failure of stent-in-stent SEMS placement.

KEYWORDS:

Endoscopic retrograde cholangiopancreatography; Endoscopic stent-in-stent self-expandable metallic stent placement; Malignant hilar biliary obstruction; Predictive factor; Self-expandable metallic stent

PMID:
28974893
PMCID:
PMC5603493
DOI:
10.3748/wjg.v23.i34.6273
[Indexed for MEDLINE]
Free PMC Article

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