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Mini Rev Med Chem. 2017 Oct 3. doi: 10.2174/1389557517666171003103245. [Epub ahead of print]

Recent Progress of Novel Steroid Derivatives and Their Potential Biological Properties.

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1
National Biopesticide Engineering Technology Research Center, Hubei Biopesticide Engineering Research Center, Hubei Academy of Agricultural Sciences, Wuhan 430064. China.

Abstract

Steroid and its derivatives have been proved to have important and diverse biological functions, which present the wide spectrum of biological activities such as antitumor, antiviral, antibacterial, antimicrobial, antifungal, antioxidant, insecticidal, aromatase inhibitors, 5α-reductase inhibitors and neuromuscular blocking agents et c. Versatile features of steroid-derived compounds have emerged, so the aim of the present paper was to review the recent advances of steroid-based derivatives mainly focused on their structures and biological properties.

KEYWORDS:

Biological properties; Derivatives; Diversity; Recent progress; Steroid; Structure

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