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Prev Med. 2018 Jan;106:38-44. doi: 10.1016/j.ypmed.2017.09.022. Epub 2017 Sep 28.

Estimating health benefits and cost-savings for achieving the Healthy People 2020 objective of reducing invasive colorectal cancer.

Author information

1
Division of Cancer Prevention and Control, U.S. Centers for Disease Control and Prevention, 4770 Buford Highway, Chamblee Bldg. 107, Chamblee, GA 30341, United States.
2
Division of Cancer Prevention and Control, U.S. Centers for Disease Control and Prevention, 4770 Buford Highway, Chamblee Bldg. 107, Chamblee, GA 30341, United States. Electronic address: dce3@cdc.gov.
3
Department of Public Health, National Cheng Kung University College of Medicine, Tainan 704, Taiwan.
4
Division of Public Health Sciences, Department of Surgery, School of Medicine, Washington University in St. Louis, St. Louis, MO 63110, United States.

Abstract

This study aims to quantify the aggregate potential life-years (LYs) saved and healthcare cost-savings if the Healthy People 2020 objective were met to reduce invasive colorectal cancer (CRC) incidence by 15%. We identified patients (n=886,380) diagnosed with invasive CRC between 2001 and 2011 from a nationally representative cancer dataset. We stratified these patients by sex, race/ethnicity, and age. Using these data and data from the 2001-2011 U.S. life tables, we estimated a survival function for each CRC group and the corresponding reference group and computed per-person LYs saved. We estimated per-person annual healthcare cost-savings using the 2008-2012 Medical Expenditure Panel Survey. We calculated aggregate LYs saved and cost-savings by multiplying the reduced number of CRC patients by the per-person LYs saved and lifetime healthcare cost-savings, respectively. We estimated an aggregate of 84,569 and 64,924 LYs saved for men and women, respectively, accounting for healthcare cost-savings of $329.3 and $294.2 million (in 2013$), respectively. Per person, we estimated 6.3 potential LYs saved related to those who developed CRC for both men and women, and healthcare cost-savings of $24,000 for men and $28,000 for women. Non-Hispanic whites and those aged 60-64 had the highest aggregate potential LYs saved and cost-savings. Achieving the HP2020 objective of reducing invasive CRC incidence by 15% by year 2020 would potentially save nearly 150,000 life-years and $624 million on healthcare costs.

KEYWORDS:

Healthy People 2020; Invasive colorectal cancer; Life years (LYs); Lifetime healthcare costs

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