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Magn Reson Imaging Clin N Am. 2017 Nov;25(4):697-704. doi: 10.1016/j.mric.2017.06.003. Epub 2017 Aug 23.

Current Radiographic Iodinated Contrast Agents.

Author information

1
Department of Radiology and Radiological Science, Medical University of South Carolina, 96 Jonathan Lucas Street MSC 323, Charleston, SC 29425, USA. Electronic address: spampin@musc.edu.
2
School of Medicine, University of South Carolina, 6311 Garners Ferry Road, Columbia, SC 29209, USA.
3
Department of Radiology and Radiological Science, Medical University of South Carolina, 96 Jonathan Lucas Street MSC 323, Charleston, SC 29425, USA.

Abstract

Millions of radiologic examinations requiring the use of iodinated contrast are performed yearly in North America. Triiodobenzoic acid, the contrast agent molecule currently in use, is a benzene ring covalently bonded to the 3 iodine atoms. Iodinated contrast media can be divided in 4 categories: ionic monomers, ionic dimers, nonionic monomer, and nonionic dimers. Currently, second- and third-generation nonionic low-osmolar and iso-osmolar contrast media are used in clinical practice. The search for a safer and more effective iodinated contrast agents remains an ongoing challenge and important research topic.

KEYWORDS:

Computed tomography; Contrast media; Digital subtraction angiography; Iodinated contrast agents; Iodine; Triiodobenzoic acid

PMID:
28964459
DOI:
10.1016/j.mric.2017.06.003
[Indexed for MEDLINE]

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