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Nat Genet. 2017 Sep 27;49(10):1419-1420. doi: 10.1038/ng.3962.

Capturing condensin in chromosomes.

Author information

1
Chromosome Dynamics Laboratory, RIKEN, Wako, Japan.

Abstract

A new study uses a Hi-C technique to demonstrate that condensin has a major role in remodeling interphase chromatin into mitotic chromosomes. This study provides insight into the mechanism whereby a centimeters-long DNA molecule is folded into a micrometers-long rod-shaped chromosome.

PMID:
28951628
DOI:
10.1038/ng.3962
[Indexed for MEDLINE]

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