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Trends Genet. 2017 Nov;33(11):832-841. doi: 10.1016/j.tig.2017.08.007. Epub 2017 Sep 22.

Revisiting the Relationship between Transposable Elements and the Eukaryotic Stress Response.

Author information

1
Institute of Evolutionary Biology, CSIC-Universitat Pompeu Fabra, Barcelona, Spain; These authors contributed equally.
2
Institute of Evolutionary Biology, CSIC-Universitat Pompeu Fabra, Barcelona, Spain. Electronic address: josefa.gonzalez@ibe.upf-csic.es.

Abstract

A relationship between transposable elements (TEs) and the eukaryotic stress response was suggested in the first publications describing TEs. Since then, it has often been assumed that TEs are activated by stress, and that this activation is often beneficial for the organism. In recent years, the availability of new high-throughput experimental techniques has allowed further interrogation of the relationship between TEs and stress. By reviewing the recent literature, we conclude that although there is evidence for a beneficial effect of TE activation under stress conditions, the relationship between TEs and the eukaryotic stress response is quite complex.

KEYWORDS:

activation; fitness effects; gene regulation; repression; silencing mechanisms

PMID:
28947157
DOI:
10.1016/j.tig.2017.08.007
[Indexed for MEDLINE]

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