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Intractable Rare Dis Res. 2017 Aug;6(3):215-218. doi: 10.5582/irdr.2017.01041.

Filarial huge splenomegaly dramatically regressed by anti-filarial medication: A rare clinical scenario.

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Department of Internal Medicine, All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Department of Radio diagnosis, All India Institute of Medical Sciences (AIIMS), New Delhi, India.


Lymphatic filariasis is caused by nematodes Wuchereria bancrofti, Brugia malayi and Brugia timori. Lymphatic filariasis is a spectrum of illness and can manifest as, asymptomatic microfilaraemia, acute lymphatic filariasis (lymphangitis and lymphoedema), chronic lymphoedema, elephantiasis, hydrocele, tropical pulmonary eosinophilia and some systemic manifestations which involves joint, heart, kidney, nerve, etc. We here present a case of huge splenomegaly caused by lymphatic filariasis which is a rare presentation and only few cases had been reported in the world literature so far. After treatment of filariasis spleen size was reduced dramatically and patient is doing well even after 6 months of follow up after therapy.


Filariasis; lymphatic; splenomegaly

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