Format

Send to

Choose Destination
J Heart Lung Transplant. 2017 Oct;36(10):1080-1086. doi: 10.1016/j.healun.2017.07.005. Epub 2017 Jul 15.

Eighth annual INTERMACS report: Special focus on framing the impact of adverse events.

Author information

1
Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama. Electronic address: jkirklin@uab.edu.
2
Department of Cardiac Surgery, University of Michigan, Ann Arbor, Michigan.
3
Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Heart and Vascular Institute, Pittsburgh, Pennsylvania.
4
Department of Medicine, Brigham & Women's Hospital, Boston, Massachusetts.
5
Department of Pediatrics, Boston Children's Hospital, Boston, Massachusetts.
6
Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama.
7
Division of Cardiovascular Diseases, Advanced Technologies and Surgery Branch, National Heart, Lung, and Blood Institute, Bethesda, Maryland.
8
Department of Medicine, Cleveland Clinic Foundation, Lerner College of Medicine, Cleveland, Ohio.

Abstract

BACKGROUND:

The Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) database now includes >20,000 patients from >180 hospitals.

METHODS:

The eighth annual report of INTERMACS updates the first decade of patient enrollment.

RESULTS:

In the current era, >95% of implants are continuous flow devices. Overall survival continues to remain >80% at 1 year and 70% at 2 years. Review of major adverse events shows minimal advantage for patients with ambulatory heart failure pre-implant. Stroke, major infection, and continued inotrope requirement during the first 3 months have a major effect on subsequent survival.

CONCLUSIONS:

Greater application of durable devices to patients with ambulatory heart failure will mandate more effective neutralization or prevention of major adverse events.

KEYWORDS:

INTERMACS; advanced heart failure; destination therapy; mechanical support; ventricular assist device

PMID:
28942782
DOI:
10.1016/j.healun.2017.07.005
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center