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Transbound Emerg Dis. 2018 May;65 Suppl 1:235-247. doi: 10.1111/tbed.12695. Epub 2017 Sep 22.

Gaps in African swine fever: Analysis and priorities.

Author information

1
Centro de Investigación en Sanidad Animal (CISA-INIA), Madrid, Spain.
2
VISAVET Center and Animal Health Department, Universidad Complutense de Madrid, Madrid, Spain.

Abstract

African swine fever (ASF) causes greater sanitary, social and economic impacts on swine herds than many other swine diseases. Although ASF was first described in 1921 and it has affected more than fifty countries in Africa, Europe and South America, several key issues about its pathogenesis, immune evasion and epidemiology remain uncertain. This article reviews the main characteristics of the causative virus, its molecular epidemiology, natural hosts, clinical features, epidemiology and control worldwide. It also identifies and prioritizes gaps in ASF from a horizontal point of view encompassing fields including molecular biology, epidemiology, prevention, diagnosis and vaccine development. The purpose of this review is to promote ASF research and enhance its control.

KEYWORDS:

African swine fever; diagnostics; disease control; emerging diseases; gaps analysis; potential vaccines; priorities

PMID:
28941208
DOI:
10.1111/tbed.12695
[Indexed for MEDLINE]

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