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Biomed Pharmacother. 2017 Nov;95:1260-1275. doi: 10.1016/j.biopha.2017.09.024. Epub 2017 Oct 6.

Green tea (Camellia sinensis) and l-theanine: Medicinal values and beneficial applications in humans-A comprehensive review.

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College of Animal Science and Technology, NW A&F University, Yangling, Shaanxi, 712100, China; Institute of Animal Sciences, Faculty of Animal Husbandry, University of Agriculture, Faisalabad, 38040, Pakistan.
Department of Clinical Pharmacy, School of Basic Medicine, and Clinical Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu Province, 211198, China; Department of Urology Surgery, Aviation General Hospital, Beijing, 100012, China.
Department of Animal Sciences, University College of Agriculture, University of Sargodha, 40100, Pakistan.
Faculty of Marine Sciences, Lasbela University of Agriculture, Water and Marine Sciences, Uthal, Balochistan, 3800, Pakistan.
Poultry Department, Faculty of Agriculture, Zagazig University, Zagazig 44511, Egypt.
Poultry Department, Faculty of Agriculture, Zagazig University, Zagazig 44511, Egypt. Electronic address:
Department of Veterinary Microbiology and Immunology, College of Veterinary Sciences, UP Pandit Deen Dayal Upadhayay Pashu Chikitsa Vigyan Vishwavidyalay Evum Go-Anusandhan Sansthan (DUVASU), Mathura, Uttar Pradesh, 281 001, India.
Department of Biochemistry and Genetics, Barkatullah University, Bhopal, 462 026 M.P., India.
Central University Laboratory, Tamil Nadu Veterinary and Animal Sciences University, Madhavaram Milk Colony, Chennai, Tamil Nadu, 600051, India.
Division of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, 243 122, Uttar Pradesh, India.
Tecnologico de Monterrey, School of Engineering and Sciences, Campus Monterrey, Ave. Eugenio Garza Sada 2501, Monterrey, N.L., CP 64849, Mexico.
Razi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran.
College of Animal Science and Technology, NW A&F University, Yangling, Shaanxi, 712100, China. Electronic address:


Green tea (Camellia sinensis) is a famous herb, and its extract has been extensively used in traditional Chinese medicinal system. In this context, several studies have revealed its health benefits and medicinal potentialities for several ailments. With ever increasing scientific knowledge, search for safer, potential and novel type of health-related supplements quest, scientists are re-directing their research interests to explore natural resources i.e. medicinal herbs/plant derived compounds. Green tea consumption has gained a special attention and popularity in the modern era of changing lifestyle. The present review is aimed to extend the current knowledge by highlighting the importance and beneficial applications of green tea in humans for safeguarding various health issues. Herein, we have extensively reviewed, analyzed, and compiled salient information on green tea from the authentic published literature available in PubMed and other scientific databases. Scientific literature evidenced that owing to the bioactive constituents including caffeine, l-theanine, polyphenols/flavonoids and other potent molecules, green tea has many pharmacological and physiological functions. It possesses multi-beneficial applications in treating various disorders of humans. This review also provides in-depth insights on the medicinal values of green tea which will be useful for researchers, medical professionals, veterinarians, nutritionists, pharmacists and pharmaceutical industry. Future research emphasis and promotional avenues are needed to explore its potential therapeutic applications for designing appropriate pharmaceuticals, complementary medicines, and effective drugs as well as popularize and propagate its multidimensional health benefits.


Beneficial uses; Green tea; Human; Medicinal importance; Therapy; l-theanine

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