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Nutrients. 2017 Jul 26;9(8). pii: E800. doi: 10.3390/nu9080800.

Dietary Composition Independent of Weight Loss in the Management of Non-Alcoholic Fatty Liver Disease.

Author information

1
Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, AB T6G 2X8, Canada. eslampar@ualberta.ca.
2
Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, AB T6G 2X8, Canada. ptandon@ualberta.ca.
3
Cirrhosis Care Clinic and CEGIIR, University of Alberta, Edmonton, AB T6G 2X8, Canada. ptandon@ualberta.ca.
4
Division of Gastroenterology, Department of Medicine, University of Calgary, Calgary, AB T6G 2X8, Canada. mkothand@ucalgary.ca.

Abstract

Poor dietary composition is an important factor in the progression of non-alcoholic fatty liver disease (NAFLD). The majority of NAFLD patients follow diets with overconsumption of simple carbohydrates, total and saturated fat, with reduced intake of dietary fiber and omega-3 rich foods. Although lifestyle modifications including weight loss and exercise remain the keystone of NAFLD management, modifying dietary composition with or without a calorie-restricted diet may also be a feasible and sustainable strategy for NAFLD treatment. In the present review article, we highlight the potential therapeutic role of a "high quality healthy diet" to improve hepatic steatosis and metabolic dysfunction in patients with NAFLD, independent of caloric restriction and weight loss. We provide a literature review evaluating the evidence behind dietary components including fiber-, meat- and omega-3-rich diets and, pending further evidence, we concur with the EASL-EASD-EASO Clinical Guidelines recommendation of the Mediterranean diet as the diet of choice in these patients.

KEYWORDS:

Mediterranean diet; dietary composition; non-alcoholic fatty liver disease

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