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Immunity. 2017 Sep 19;47(3):393-395. doi: 10.1016/j.immuni.2017.08.013.

Developing Neutrophils Must Eat…Themselves!

Author information

1
Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle Drive, La Jolla, CA 92037, USA.
2
Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle Drive, La Jolla, CA 92037, USA; Department of Bioengineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA. Electronic address: klaus@lji.org.

Abstract

In this issue of Immunity, Riffelmacher et al. (2017) show that autophagy is necessary for the release of free fatty acids from intracellular stores within neutrophil precursor cells. This limits glycolysis, increases oxidative phosphorylation, and is essential for neutrophil maturation.

PMID:
28930652
DOI:
10.1016/j.immuni.2017.08.013
[Indexed for MEDLINE]
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