Format

Send to

Choose Destination
Acta Med Port. 2017 Aug 31;30(7-8):517-523. doi: 10.20344/amp.8963. Epub 2017 Aug 31.

Treatment of Anorexia Nervosa: The Importance of Disease Progression in the Prognosis.

Author information

1
Faculdade de Medicina. Universidade do Porto. Porto. Portugal.
2
Department of Community Medicine, Information and Health Decision Sciences (MEDCIDS). Facultade de Medicina. Universidade do Porto. Porto. Portugal; Centro de Investigação em Tecnologias e Serviços de Saúde (CINTESIS). Porto. Portugal.
3
Department of Psychiatry and Mental Health. Centro Hospitalar de São João. Porto. Portugal.
4
Faculdade de Medicina. Universidade do Porto. Porto. Portugal; Department of Psychiatry and Mental Health. Centro Hospitalar de São João. Porto. Portugal.

Abstract

in English, Portuguese

INTRODUCTION:

Anorexia nervosa is a severe, usually chronic, life-threatening disease of complex etiology characterized by food restriction, overestimation of the importance of body weight and image, intense fear of weight gain and distortion of body image. Anorexia nervosa is associated with high rates of mortality, suicide and decreased quality of life. Our aim is to present an anorexia nervosa treatment program offered in a major university hospital in Portugal, and to determine the impact of illness duration before admission on the outcome. Our hypothesis is that patients with greater disease longevity may have worse prognosis and poorer outcome.

MATERIAL AND METHODS:

The sample included data from case records of 169 patients seen consecutively and for the first time at Centro Hospitalar São João, between 2010 and 2015. We performed a retrospective observational study which included data collected at admission and from later follow-up years.

RESULTS:

From the initially selected patients, 14.8% reached total remission, 16% accomplished partial remission and 14.2% ended up with exacerbation/stagnation of the disease. The dropout rate was of 55% throughout our study period. We found significant differences on outcome rates between distinct illness duration groups (p = 0.007).

DISCUSSION:

There are several factors frequently associated with poor outcome for anorexia nervosa. The interpretation of outcome findings was limited by the high rate of dropout and lack of consistent definition criteria.

CONCLUSION:

Our results support the idea that illness duration has an important role on the outcome and prognostic features of these patients.

KEYWORDS:

Anorexia Nervosa/therapy; Disease Progression; Prognosis; Treatment Outcome

PMID:
28926324
DOI:
10.20344/amp.8963
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Ordem dos Medicos / Portuguese Medical Association
Loading ...
Support Center