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AJNR Am J Neuroradiol. 2018 Jan;39(1):97-101. doi: 10.3174/ajnr.A5374. Epub 2017 Sep 14.

Association of Developmental Venous Anomalies with Demyelinating Lesions in Patients with Multiple Sclerosis.

Author information

1
From the Department of Radiology and Imaging Science, University of Utah Medical Center, Salt Lake City, Utah. Douglas.rogers@hsc.utah.edu.
2
From the Department of Radiology and Imaging Science, University of Utah Medical Center, Salt Lake City, Utah.

Abstract

We present 5 cases of demyelination in patients diagnosed with multiple sclerosis that are closely associated with a developmental venous anomaly. Although the presence of a central vein is a known phenomenon with multiple sclerosis plaques, demyelination occurring around developmental venous anomalies is an underreported phenomenon. Tumefactive demyelination can cause a diagnostic dilemma because of its overlapping imaging findings with central nervous system neoplasm. The relationship of a tumefactive plaque with a central vein can be diagnostically useful, and we suggest that if such a lesion is closely associated with a developmental venous anomaly, an inflammatory or demyelinating etiology should be a leading consideration.

PMID:
28912286
DOI:
10.3174/ajnr.A5374

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