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Infect Dis Clin North Am. 2017 Dec;31(4):839-870. doi: 10.1016/j.idc.2017.07.012. Epub 2017 Sep 12.

Norovirus Infection in Older Adults: Epidemiology, Risk Factors, and Opportunities for Prevention and Control.

Author information

1
Viral Gastroenteritis Branch (proposed), Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: iyk8@cdc.gov.
2
Viral Gastroenteritis Branch (proposed), Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Abstract

Norovirus is the leading cause of acute gastroenteritis. In older adults, it is responsible for an estimated 3.7 million illnesses; 320,000 outpatient visits; 69,000 emergency department visits; 39,000 hospitalizations; and 960 deaths annually in the United States. Older adults are particularly at risk for severe outcomes, including prolonged symptoms and death. Long-term care facilities and hospitals are the most common settings for norovirus outbreaks in developed countries. Diagnostic platforms are expanding. Several norovirus vaccines in clinical trials have the potential to reap benefits. This review summarizes current knowledge on norovirus infection in older adults.

KEYWORDS:

Gastroenteritis; Long-term care; Norovirus; Older adults; Vaccine

PMID:
28911830
PMCID:
PMC6546097
DOI:
10.1016/j.idc.2017.07.012
[Indexed for MEDLINE]
Free PMC Article

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