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J Neurosci. 1987 Nov;7(11):3793-802.

Quantitative distribution of the glycine receptor in the auditory brain stem of the gerbil.

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1
Department of Neuroscience, University of Virginia Medical Center, Charlottesville 22908.

Abstract

The concentration and relative distribution of glycine receptors were determined for gerbil brain stem auditory nuclei using 3H-strychnine and quantitative autoradiographic techniques. Significant binding was observed in the anteroventral cochlear nucleus, the dorsal cochlear nucleus, the lateral superior olivary nucleus, and the inferior colliculus. A non-uniform distribution of binding was seen in 3 of these nuclei, such that the greatest concentration of glycine receptors was located in the high-frequency regions. An analysis of neuron soma density suggested that the amount of post-synaptic membrane could partially explain the distribution of receptor.

PMID:
2890726
[Indexed for MEDLINE]
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